Abstract
Terahertz imaging and spectroscopy characterization of freshly excised
breast cancer tumors are presented in the range 0.15 to 3.5 THz. Cancerous
breast tissues were obtained from partial or full removal of malignant tumors
while healthy breast tissues were obtained from breast reduction surgeries. The
reflection spectroscopy to obtain the refractive index and absorption
coefficient is performed on experimental data at each pixel of the tissue,
forming tomographic images. The transmission spectroscopy of the refractive
index and absorption coefficient are retrieved from experimental data at few
tissue points. The average refractive index and absorption coefficients for
cancer, fat, and collagen tissue regions are compared between transmission and
reflection modes. The reflection mode offers the advantage of retrieving the
electrical properties across a significantly greater number of points without
the need for sectioning or altering the freshly excised tissue as in the
transmission mode. The terahertz spectral power images and the tomographic
images demonstrated good qualitative comparison with pathology.
for full paper see https://www.spiedigitallibrary.org/journals/Journal-of-Medical-Imaging/volume-6/issue-2/023501/Terahertz-tomographic-imaging-of-freshly-excised-human-breast-tissues/10.1117/1.JMI.6.2.023501.short
The spectroscopy and imaging procedures in this work were performed using
the TPS Spectra 3000 pulsed THz imaging and spectroscopy system (from TeraViewLtd., United Kingdom) at the University of Arkansas; system details are shown in Ref. 16
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