Wednesday, 21 February 2018

Pulsed terahertz imaging of breast cancer in freshly excised murine tumors

Bowman, Tyler, Tanny Chavez, Kamrul Khan, Jingxian Wu, Avishek Chakraborty, Narasimhan Rajaram, Keith Bailey, and Magda El-Shenawee. "Pulsed terahertz imaging of breast cancer in freshly excised murine tumors." Journal of Biomedical Optics 23, no. 2 (2018): 026004.


This paper investigates terahertz (THz) imaging and classification of freshly excised murine xenograft breast cancer tumors. These tumors are grown via injection of E0771 breast adenocarcinoma cells into the flank of mice maintained on high-fat diet. Within 1 h of excision, the tumor and adjacent tissues are imaged using a pulsed THz system in the reflection mode. The THz images are classified using a statistical Bayesian mixture model with unsupervised and supervised approaches. Correlation with digitized pathology images is conducted using classification images assigned by a modal class decision rule. The corresponding receiver operating characteristic curves are obtained based on the classification results. A total of 13 tumor samples obtained from 9 tumors are investigated. The results show good correlation of THz images with pathology results in all samples of cancer and fat tissues. For tumor samples of cancer, fat, and muscle tissues, THz images show reasonable correlation with pathology where the primary challenge lies in the overlapping dielectric properties of cancer and muscle tissues. The use of a supervised regression approach shows improvement in the classification images although not consistently in all tissue regions. Advancing THz imaging of breast tumors from mice and the development of accurate statistical models will ultimately progress the technique for the assessment of human breast tumor margins

"This work makes use of the TPS Spectra 3000 THz pulsed imaging and spectroscopy system (TeraView, Ltd., United Kingdom) at the University of Arkansas."

For more information about TeraView see

For full paper see

Monday, 19 February 2018

The 9th International Symposium on Ultrafast Phenomena and Terahertz Waves (ISUPTW 2018)

On behalf of the Program Committee, we are pleased to announce that The 9th International Symposium on Ultrafast Phenomena and Terahertz Waves (ISUPTW 2018) will be held in Changsha, China from April 23 to 26, 2018. ISUPTW 2018 is organized by National University of Denfense Technology (NUDT) and the Optical Society of America (OSA). More information will be released in the website.

ISUPTW, an international symposium, is devoted to strengthening the collaboration among worldwide researchers and promoting the development in Ultrafast and Terahertz science and technology. The biennial symposium, initiated in 2002, has been held in Beijing, Shanghai, Nanjing, Tianjin, Xi'an, and Wuhan. It brings together scientists, technologists, and students from more than 10 countries and typically hosts 150-300 participants.

This symposium provides an excellent opportunity to share and exchange ideas. We look forward to welcoming our friends and colleagues from all around the world. The paper submission system is open now. We warmly invite you and your colleagues as well as students to submit the latest work. The contributed papers will be archived on EI Compendex by OSA. We believe you will not only enjoy the exchange and discussions on ultrafast phenomena and terahertz wave, but will also have a memorable experience in Changsha, China.

It is our great pleasure to invite you to attend this symposium.Your contributions are crucial to the success of these exciting events.

We look forward to seeing you in Changsha, China.

Topics may include, but are not limited to:
Symposium I: The development of ultrafast phenomena and ultrashort pulse laser
1. Ultrafast science and technology;
2. Ultrafast phenomena in micro and nano-structures;
3. High-speed diagnosis, high-speed imaging, and high-speed data processing etc;
4. High-field physics and attosecond science;
5. Ultra high intensity laser and its application;
Symposium II: Terahertz science and technology 1. Extreme terahertz science and technology;
2. Terahertz science and technology in micro and nano-structures;
3. Terahertz spectroscopy and the interaction between terahertz radiation and materials.
4. Terahertz wave transmission and communication;
5. Terahertz imaging and its application;
6. The applications of terahertz wave in industry, defense, and astronomy.

for more information see

8th International Workshop on Terahertz Technology and Applications

March 20th/21st 2018 in Kaiserslautern (Germany)

7th Workshop on Terahertz Technology and Applications (Bild: VDI e.V.)
8th International Workshop on Terahertz Technology and Applications

Nowadays terahertz technology has proven to be a valuable tool for applications in diagnostics, measurement and testing. The industrial use of this technology, however, puts a lot of challenging questions. The 8th “International Workshop on Terahertz Technology and Applications” especially fosters the exchange of knowledge and experience between academics and industry in this exciting and rapidly developing field.

The workshop will address primarily the topics:
  1. Non-destructive testing
  2. Technology for homeland security
  3. Communications
  4. Health and social aspects of terahertz technology
  5. New THz system Technologies

The workshop is focused on the subjects below:
  • sources and detectors,
  • imaging and
  • millimeter-wave testing.

It also addresses:
  • spectroscopy,
  • communication,
  • coatings and
  • regulative aspects of Terahertz radiation.

The international workshop is jointly organised by VDI/VDE Society Measurement and Automatic Control and Fraunhofer ITWM. 

for more information see

Friday, 16 February 2018

Call for Papers – 43rd International Conference on Infrared, Millimeter and Terahertz Waves

We are very happy to announce that the 43rd International Conference on Infrared, 
Millimeter and Terahertz Waves (IRMMW-THz 2018) is now open for accepting submissions
of one-page abstracts. The deadline is March 31st, 2018.

IRMMW-THz 2018 will be held in Nagoya, Japan during September 9-14, 2018.
The conference venue is Nagoya Congress Center. Nagoya city is the 4th largest city in Japan,
and the venue is located within 4 km (or 10 min by train) from the downtown of the city.
The access from the Chubu Centrair International Airport in Nagoya is very convenient,
and it takes about 30-40 minutes by the express trains. For more detail,
please visit our website

Topics at the conference include, but are not strictly limited to:
1.    Astronomy, Planetary and Environmental Science
2.    Applications in Biology and Medicine
3.    Applications in Industry, Security and Inspection
4.    Spectroscopy and Material Properties
5.    Spectroscopy of Gases, Liquids, and Solids
6.    Sources, Detectors, and Receivers
7.    Imaging and Remote Sensing
8.    Modeling and Analysis Techniques
9.    Metamaterial Structures and Applications
10.    Devices, Components, and Systems
11.    High-Field THz Wave Generation and Nonlinear THz Physics
12.    MM and sub-MM wave systems
13.    Laser Driven THz Sources
14.    Quantum Cascade Lasers
15.    Gyro-Oscillators and Amplifiers
16.    Free Electron Lasers and Synchrotron Radiation
17.    Ultrafast Measurements
18.    Metrology
19.    MMW and THz Wave Radar and Communications
20.    2D Materials for MMW, THz, IR Applications

We are very much looking forward to welcoming you to Nagoya for a week
with 300+ exciting talks and plentiful poster sessions reporting on the latest advances in this field,
as well as technical exhibits with the newest THz technology and networking with your old and
new colleagues in the largest forum for IR, millimeter and terahertz wave science and technology !

Best wishes

Dr. Toshitaka Idehara
Dr. Masahiko Tani
Chairs of IRMMW-THz 2018 (Nagoya, Japan)

Tuesday, 13 February 2018

Presentation at IFPAC 2018

Dissolution Modeling of a Controlled Release Osmotic Tablet using Terahertz Pulsed Imaging (TPI): A Chemometric Approach 

Zach Dance1, Brian Regler1, Donna Carroll1, Busolo Wabuyele1, Jerry Klinzing1, Jim DiNunzio1, Gary Chia1, Lee Dowden1, Gerard Bredael1, David Harris1, Zhihao Lin1, Phil Taday2
[1Merck & Co., Inc., 2TeraView Ltd.]



Push-pull osmotic tablets are currently being developed for controlled release of compound A in order to provide once daily dosing. The release rate of compound A from the osmotic tablet has been found to be largely controlled by the coating thickness. Terahertz pulsed imaging (TPI) uses short pulses of terahertz radiation (2-120 cm-1) that penetrate typical pharmaceutical components. The time delay of reflections of these pulses from materials of different refractive indexes in the sample allows for the measurement of thickness of various materials. Using TPI, the coating thickness of compound A osmotic tablets can be measured in a rapid, non-destructive manner across an entire tablet. The coating thickness data obtained using TPI was found to be in line with other analysis techniques such as XRCT. Combining the dissolution release rate data from products designed to provide different drug release rates through modification of coating weight, a chemometric model was developed to predict release rate as a function of coating thickness.