TeraView's Dr. Philip Taday will be attending 'Technisches Kolloquium' - 26th of November 2014

TeraView are happy to announce that we will be attending Technisches Kolloquium - Terahertz technology for NDT

'Technisches Kolloquium - Terahertz technology for NDT will be held on the 26th of November 2014 in the conference/class room in Zorneding, Munich.

This event will be open to all our customers and to contacts of our partner Allianz.'


The event is free of charge and will be attended by Dr. Philip Taday who will be presenting a talk on: 
“Applications of terahertz pulsed technology in non-destructive testing”

Evaluation of critical process parameters for inter-tablet coating uniformity of active-coated GITS using Terahertz Pulsed Imaging

Daniela Brock, J. Axel Zeitler, Adrian Funke, Klaus Knop, Peter Kleinebudde

Abstract

The aim of this study was the evaluation of critical process parameters (CPP) for inter-tablet coating uniformity in an active pan coating process using nondestructive Terahertz Pulsed Imaging (TPI). Coating uniformity was assessed by calculating the coefficient of variation (CV) of coating thickness measured by TPI, and the CV of API content measured by high performance liquid chromatography (HPLC). A design of experiments (DoE) was performed at pilot scale with drum load, drum speed, spray rate, run duration and spray pressure as factors. Good agreement in the CV of both analytical techniques was shown. The DoE models both revealed the same CPP: a low drum load, high drum speed, low spray rate and high run duration were beneficial for coating uniformity. The spray pressure was only significant in one of the DoE models. It was further shown that the negative impact of a high drum load on the CV cannot only be compensated by high drum speed, but also be compensated by a low spray rate and long run duration. It was demonstrated that TPI is a feasible tool for the measurement of inter-tablet coating uniformity and for the evaluation of CPP in an active pan coating process.

This study was performed using TeraView's Imaga 2000 system. (TeraView, Cambridge, UK)

Full Article: http://www.sciencedirect.com/science/article/pii/S0939641114002203

Terahertz spectroscopy for the characterization of excised human breast tissue

Bowman, Tyler ; El-Shenawee, Magda ; Sharma, Shree G.

Abstract

This paper presents experimental terahertz spectroscopy measurements of normal and breast cancer tissue in the range 0.1 to 4 THz. Both tissue types are prepared on microscope glass and polystyrene slides. The preliminary results of a particular tumor tissue using terahertz spectroscopy align with the pathology diagnosis of poorly differentiated tumor. The results demonstrate the potential of terahertz spectroscopy for the characterization of cancer, fibro, and normal breast tissue. More research into the sample thickness, microscopic slide material, embedding medium and cancer type will be presented using a large number of samples in order to establish the technique.

This study was performed using TeraView's TPS spectra 3000 system. (TeraView, Cambridge, UK)

Full Article: http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=6848538&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D6848538

Use of Finite Difference Time Domain Simulations and Debye Theory for Modelling the Terahertz Reflection Response of Normal and Tumour Breast Tissue

Anthony J. Fitzgerald, Emma Pickwell-MacPherson, Vincent P. Wallace

Abstract

The aim of this work was to evaluate the capabilities of Debye theory combined with Finite Difference Time Domain (FDTD) methods to simulate the terahertz (THz) response of breast tissues. Being able to accurately model breast tissues in the THz regime would facilitate the understanding of image contrast parameters used in THz imaging of breast cancer. As a test case, the model was first validated using liquid water and simulated reflection pulses were compared to experimental measured pulses with very good agreement (p = 1.00). The responses of normal and cancerous breast tissues were simulated with Debye properties and the correlation with measured data was still high for tumour (p = 0.98) and less so for normal breast (p = 0.82). Sections of the time domain pulses showed clear differences that were also evident in the comparison of pulse parameter values. These deviations may arise from the presence of adipose and other inhomogeneities in the breast tissue that are not accounted for when using the Debye model. In conclusion, the study demonstrates the power of the model for simulating THz reflection imaging; however, for biological tissues extra Debye terms or a more detailed theory may be required to link THz image contrast to physiological composition and structural changes of breast tissue associated with differences between normal and tumour tissues.

This study was performed using TeraView's TPS spectra 1000 system. (TeraView, Cambridge, UK)

Full Article: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0099291#pone-0099291-g005

Position at TeraView - Business Development Manager

TeraView Limited is the world's leader in the design and manufacture of terahertz (THz) products to the pharmaceutical, security, medical and materials characterisation markets. Our products continue to yield many ground-breaking applications such as tablet coating thickness and uniformity, cracks, defect analysis, foreign materials and analysis of solid-state structure to be exploited by our customers. Based in Cambridge UK, we have a global client base and a highly-skilled workforce.

We are seeking a Business Development Manager to join our team; an individual who is able to meet the existing operational needs of the company, as well as planning for the future needs of the company as we grow. 

TeraView is the world's leading terahertz company. Established in 2001, as a spin out from the Toshiba laboratories in Cambridge the company is focused on the application of terahertz technology.

For a full job description and 

other information on the role, please visit: http://www.teraview.com/about/careers-jobs.html

Terahertz time-domain spectroscopy for measurement of particle sizes of fexofenadine hydrochloride

Anna Sadloňová, Vojtech Kresalek, Tomas Bata

Abstract

Time domain spectroscopy is one of the new methods of terahertz radiation used for wide spectrum of the industry. More extended sector is the security system much like the sector of the medicine. The main focus is orientated to detection and identification of the substances. This study is focused on the measurement of the particle size of pharmaceuticals. The characteristic absorption features will be studied experimentally by Terahertz time-domain spectroscopy. The results are identified for processing by one of the statistical method usable for such variable groups. The three samples of the pharmaceutical– Fexofenadine Hydrochloride (antihistamine) will be compared between themselves. Mentioned samples are supplied by different suppliers. The main focus will be put on the pharmaceutical differences of the same pharmaceutical that are commonly available on the markets. Terahertz time-domain spectroscopy setup was used to measure absorbance spectra of each sample in the range from 1 THz to 3 THz (it was used the device TPS Spectra 3000 produced by TeraView Ltd . The device that belongs to the first commercial machine developed in this company for measurement of the substances by transmission spectroscopy method.). During the testing was used the vacuum for purging the measurement chamber from water vapors.

This study was performed using TeraView's TPS spectra 3000 system. (TeraView, Cambridge, UK)

Full Article: http://spie.org/ESD/conferencedetails/millimetre-wave-and-terahertz-sensors-and-technology

Distinguishing of different kinds of gunpowder using various methods based on Terahertz radiation

Tomáš Gavenda, Vojtech Kresalek, Tomas Bata

Abstract

The research performed by authors of this article in the year 2013 [1] lead to the following presented research. Different samples of commercially known kinds of gunpowder prepared by various manufactures were measured to obtain presented data. The article published in 2013 [1] proved, that particular samples can be distinguished from each other using terahertz time-domain spectroscopy. This article presents results of measuring and analysing of gunpowder samples using other methods based on terahertz radiation. Ten different samples of gunpowder were measured during the research. Most of them were based on nitrocellulose, but components of each sample differ. Systems TPS Spectra 3000 by TeraView Ltd. and Tera OSCAT by Menlo GmbH. were used for measurements. Several terahertz radiation based methods were used for researching the possibility of distinguishing different kinds of gunpowder, such as terahertz imaging (using both transitive and reflective imaging method), ATR spectroscopy and reflective variant of time-domain spectroscopy. Frequency ranges differ in dependence on used method, but the range from 0.5 THz to 2.0 THz was measured mostly. Presented research also contains results of measurements of gunpowder compounds, for example compounds with polymer materials (like polyethylene). These measurements are important because of the need for development of new possibilities to detect and identify dangerous materials at airports or other public places. Main contribution of this research is extension of knowledge in the domain of detection, identification and distinguishing of different kinds of gunpowder, which are commercially available and therefore exploitable as dangerous explosive materials. This article, together with the previous presented and already published article [1], makes comprehensive result of gunpowder properties measurement using methods based on terahertz radiation. [1] Gavenda T., Kresalek V., “Terahertz time-domain spectroscopy for distinguishing different kinds of gunpowder,” Proc. SPIE 8900, 6 pages (2013).

This study was performed using TeraView's TPS spectra 3000 system. (TeraView, Cambridge, UK)

Full Article: http://spie.org/ESD/conferencedetails/millimetre-wave-and-terahertz-sensors-and-technology

Tuning characteristics of mirrorlike T-shape terahertz metamaterial using out-of-plane actuated cantilevers

Yu-Sheng Lin and Chengkuo Lee

Abstract

We present a mirrorlike T-shape metamaterial (MTM) with out-of-plane movable microstructures for enabling active tuning of resonant frequency in the terahertz (THz) region. The resonant frequency of MTM device can be actively controlled by using either electrostaticforce or liquid force. First, by gradually increasing the bias, the cantilevers were continuously deformed towards the substrate and then completely snapped down when the bias reached the critical pull-in voltage (12 V). The tuning range is 0.50 THz as compared to the devicewithout driving voltage to that operated at the pull-in voltage. Meanwhile, we dropped different liquids on the snap-down device surface. In the case of device covered with deionised water, the resonant frequency shift of 0.17 and 0.21 THz were measured for inductive-capacitive and dipolar resonances, respectively. Furthermore, we also demonstrate the flow tuning capability of MTM device integrated with a polydimethylsiloxane fluidic channel by using different injection flow rate from 0 to 5 ml/min. The tunability of MTM device is 0.30 THz due to the different bending states of the MTM cantilevers under different liquid forces.

This study was performed using TeraView's TPS spectra 3000 system. (TeraView, Cambridge, UK)

Full Article: http://scitation.aip.org/content/aip/journal/apl/104/25/10.1063/1.4885839