Advancing in-vivo terahertz imaging

Emma Pickwell-MacPherson

New developments in terahertz frequency imaging make it suited to assist in patient screening and diagnosis.

7 February 2011, SPIE Newsroom. DOI: 10.1117/2.1201012.003437

Terahertz (10¹²Hz, THz) frequency radiation lies between the IR and millimeter regions of the electromagnetic spectrum (1THz corresponds to 33.3cm⁻¹, 4.14meV, and has a wavelength of 300μm). Historically, terahertz wave generation was a challenge. Various methods to extend optical techniques to lower frequencies or to ramp up electronic techniques to higher frequencies have been explored. Significant advances in the field mean that presently, numerous companies sell systems and components worldwide (see Figure 1). As generating terahertz radiation is no longer a hurdle, the interest now lies in finding potential applications for this radiation.

For the rest of the story see http://spie.org/x44146.xml?highlight=x2416&ArticleID=x44146

To see TeraView's full range of products see http://www.teraview.com/products/index.html

New frontiers for commercial applications of terahertz

Aerospace and Electronics Conference (NAECON), Proceedings of the 2011 IEEE National


Date of Conference: 20-22 July 2011
Author(s): Yeo, Woon-Gi
ElectroScience Laboratory, Electrical and Computer Engineering Dept., The Ohio State University, Columbus, OH 43212
Nahar, Niru K. ;  Lee, Robert ;  Volakis, John L. 


ABSTRACT

We present several preliminary experimental data to demonstrate the potential of terahertz imaging for various commercial applications. Specifically, terahertz images and signatures are presented using terahertz pulsed imaging (TPI™) for green leaves, lung cancer tissues, as well as farm and wild raised salmons. Raw data from these measurements provided the associated refractive indices and absorption coefficients. Time domain reflectometry (TDR) signatures were also collected at terahertz frequencies for integrated circuits. This was done using an electro-optic terahertz pulse reflectometry (EOTPR) system. In all cases, it is demonstrated that discriminatory information can be readily obtained from terahertz images or TDR signals for various organic and non-organic materials.

For more information about EOTPR see http://www.teraview.com/applications/semiconductor/terahertz-pulsed-reflectometry.html

For more information terahertz applications see

http://www.teraview.com/applications/index.html

THz papers at CLEO 2012

For  anyone who is interested in terahertz applications and is attending CLEO 2012 next week


6-11th May 2012


San Jose Convention Center, San Jose, CA


For information see http://www.cleoconference.org/home.aspx

The following terahertz talks may be of interest - if anyone would like to write a report on these terahertz sessions at this conference we will be happy to post here.  We have selected these talks just out of interest.

TITLE: Generation of ultrabroadband coherent infrared wave with 200 THz bandwidth using air plasma driven by intense sub 10 fs pulses

AUTHORS (FIRST NAME, LAST NAME): Eiichi Matsubara1, Masaya Nagai1, Masaaki Ashida1

INSTITUTIONS (ALL): 1. Osaka university, Toyonaka, Japan.

ABSTRACT BODY: Abstract (35 Word Limit): We demonstrated the generation of infrared wave exceeding 200 THz through air plasma using sub-10-fs pulses produced by hollow fiber compression. Electro-optic sampling with 20-μm GaSe crystal assures the wave is coherent. TITLE: High Field THz Pulse Generation and Nonlinear THz Dynamics AUTHORS (FIRST NAME, LAST NAME): Frank Hegmann1 INSTITUTIONS (ALL): 1. University of Alberta, Alberta, AB, Canada. ABSTRACT BODY: Abstract (35 Word Limit): The generation of intense single-cycle THz pulses and their application to the study of ultrafast nonlinear THz dynamics in semiconductors, such as terahertz-pulse-induced intervalley scattering and hot electron effective mass anisotropy, are described. TITLE: Highly efficient generation of single-cycle MV/cm THz pulses in organic crystals AUTHORS (FIRST NAME, LAST NAME): Clemens Ruchert1, Carlo Vicario1, Fernando Ardana1, Christoph P. Hauri1 INSTITUTIONS (ALL): 1. Paul Scherrer Institute, Villigen PSI, Switzerland. ABSTRACT BODY: Abstract (35 Word Limit): We present the generation of high-power single-cycle THz pulses in organic salt crystals. Broadband THz radiation with MV/cm electric field strength is produced by optical rectification driven with a powerful femtosecond optical parametric amplifier. TITLE: Fiber Drawn 2D Polymeric Photonic Crystal THz Filters AUTHORS (FIRST NAME, LAST NAME): Matthias Stecher1, 4, Christian Jansen1, Mehdi Ahmadi-Boroujeni1, Richard Lwin2, Alessio Stefani3, Ole Bang3, Martin Koch1, Graham E. Town4 INSTITUTIONS (ALL): 1. AG Exp. Halbleiterphysik, Philipps-Universität Marburg, Marburg, Germany. 2. Institute of Photonics and Optical Science (IPOS), School of Physics, The University of Sydney, Sydney, NSW, Australia. 3. DTU Fotonik, Department of Photonics Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark. 4. Department of Electronic Engineering, Macquarie University, Sydney, NSW, Australia. ABSTRACT BODY: Abstract (35 Word Limit): We report on polymeric 2D photonic crystal filters for THz frequencies fabricated by a standard fiber drawing technique. The frequency and angle dependent transmission spectra were characterized in a pulsed terahertz (THz) time domain spectrometer. TITLE: THz control of matter states: Coherent excitons beyond the Rabi-splitting AUTHORS (FIRST NAME, LAST NAME): Benjamin Ewers1, Niko S. Koester1, Ronja Woscholski1, Martin Koch1, Sangam Chatterjee1, Galina Khitrova2, Hyatt M. Gibbs2, Andrea C. Klettke1, Mackillo Kira1, Stephan W. Koch1 INSTITUTIONS (ALL): 1. Faculty of Physics and Materials Sciences Center, Philipps-Universität Marburg, Marburg, Germany. 2. College of Optical Sciences, The University of Arizona, Tucson, AZ, United States. ABSTRACT BODY: Abstract (35 Word Limit): We investigate the interaction of strong single-cycle THz pulses with a coherent excitonic population, observing the transition from Rabi flopping of the 1s-2p transition to multi THz-photon ionization with increasing field strength. TITLE: Nonlinear THz spectroscopy of graphene AUTHORS (FIRST NAME, LAST NAME): Pamela Bowlan1, Elias Martinez-Moreno1, Klaus Reimann1, Michael Woerner1, Thomas Elsaesser1 INSTITUTIONS (ALL): 1. Max-Born-Institut, Berlin, Germany. ABSTRACT BODY: Abstract (35 Word Limit): Carrier dynamics in graphene at low energies are studied using two-dimensional THz spectroscopy. Pump-probe signals much faster than the acoustic phonon energy are observed due to a combination of intra- and interband absorption. TITLE: THz Metrological Traceability and Suitable Detectors AUTHORS (FIRST NAME, LAST NAME): Ralf Müller1, Werner Bohmeyer2, Karsten Lange2, Andreas Steiger1 INSTITUTIONS (ALL): 1. Physikalisch-Technische Bundesanstalt (PTB), Berlin, Berlin, Germany. 2. Sensor- und Lasertechnik (SLT), Neuenhagen, Brandenburg, Germany. ABSTRACT BODY: Abstract (35 Word Limit): PTB, the metrology institute of Germany, operates the worldwide first and still unique THz detector calibration facility traceable to SI. A project in cooperation with SLT company is dedicated to develop suitable pyroelectric THz detectors.

Top Downloads in Imaging Systems from OSA

View JOSA A Top Downloads in Imaging Systems OSA’s Journal of the Optical Society of America A (JOSA A) publishes essential research from a wide variety of topic areas in optics and photonics. This year we (OSA) will showcase some of JOSA A’s best research from a few of these areas. The email below highlights top downloaded articles in Imaging Systems over the last two years. To ensure that these articles can be broadly accessed by subscribers and non-subscribers alike, we have made these articles free to access until June 30.  Please feel free to forward the e-mail on to others who may be interested in this topic area. Three-dimensional imaging of optically opaque materials using nonionizing terahertz radiation Abstract | Full Text: PDF | JOSA A, Vol. 25 Issue 12, pp.3120-3133 (2008) Wallace, Vincent P; MacPherson, Emma; Zeitler, J Axel; Reid, Caroline Terahertz electromagnetic radiation has already been shown to have a wide number of uses. We consider specific applications of terahertz time-domain imaging that are inherently three-dimensional. This paper highlights the ability of terahertz radiation to reveal subsurface information as we... Full-Text PDF contains links to datasets. See ISP homepage for software requirements and other information. Editor's Note:  Other non-terahertz papers were also highlighted by OSA but not copied here. To learn more about TeraView's products visit http://www.teraview.com/products/index.html

Probing biological systems with terahertz spectroscopy

12 - 16 August 2012 San Diego Convention Center San Diego, CA United States  Conference 8496 Terahertz Emitters, Receivers, and Applications III Conference Program Track: Photonic Devices and Applications Available in print as Proceedings of SPIE Volume 8496 Dates: Sunday-Monday 12 - 13 August 2012 Conference Chairs Manijeh Razeghi, Northwestern Univ.; Alexei N. Baranov, Univ. Montpellier 2 (France); Henry O. Everitt, U.S. Army Aviation and Missile Research Development and Engineering Ctr.; John M. Zavada, National Science Foundation; Tariq Manzur, Naval Undersea Warfare Ctr. Program Committee Stefano Barbieri, Lab. Matériaux et Phénomènes Quantiques, CNRS, Univ. Paris 7-Denis Diderot (France); Daniel Dolfi, Thales Research & Technology (France); Jérôme Faist, ETH Zurich (Switzerland); Mauro Fernandes Pereira, Jr., Sheffield Hallam Univ. (United Kingdom); Guido Giuliani, Univ. degli Studi di Pavia (Italy); Qing Hu, Massachusetts Institute of Technology; M. Quamrul Huda, Univ. of Alberta (Canada); Gaël Mouret, Univ. du Littoral Côte d'Opale (France); Gregory S. Nusinovich, Univ. of Maryland, College Park; Carlo Sirtori, Univ. Paris 7-Denis Diderot (France); Zachary D. Taylor, Univ. of California, Los Angeles; Gintaras Valusis, Ctr. for Physical Sciences and Technology (Lithuania); Miriam S. Vitiello, Consiglio Nazionale delle Ricerche (Italy) Probing biological systems with terahertz spectroscopy  (Invited Paper)   Paper 8496-26 Author(s): Emma Pickwell-MacPherson, Hong Kong Univ. of Science and Technology (Hong Kong, China); Edward P. Parrott, The Chinese Univ. of Hong Kong (Hong Kong, China); Yiwen Sun, Shenzhen Univ. (China) Terahertz spectroscopy is able to probe several aspects of biological systems. Most well known is its sensitivity to water due to the strong water absorptions at terahertz frequencies. However an increasing number of studies have shown that it is not just water content that terahertz is sensitive to and that other factors such as tissue structure, molecular arrangement or even temperature can also affect the signal. In this talk examples ranging from breast cancer spectroscopy to antibody protein spectroscopy will be discussed. For more information visit http://spie.org/optics-photonics.xml?WT.mc_id=ROP12GB